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Benefits from Immunization During the Vaccines for Children Program Era - United States, 1994 - 2013 Benefits from Immunization During the Vaccines for Children Program Era — United States, 1994–2013. Cynthia G. Whitney, MD 1Fangjun Zhou, PhD 2James Singleton, PhD 2Anne Schuchat, MD 1 (Author affiliations at end of text) The Vaccines for Children (VFC) program was created by the Omnibus Budget Reconciliation Act of 1993 ( 1 ) and first implemented in 1994. VFC was designed to ensure that eligible children do not contract vaccine-preventable diseases because of inability to pay for vaccine and was created in response to a measles resurgence in the United States that resulted in approximately 55,000 cases reported during 1989–1991 ( 2 ). The resurgence was caused largely by widespread failure to vaccinate uninsured children at the recommended age of 12–15 months. To summarize the impact of the U.S. immunization program on the health of all children (both VFC-eligible and not VFC-eligible) who were born during the 20 years since VFC began, CDC used information on immunization coverage from the National Immunization Survey (NIS) and a previously published cost-benefit model to estimate illnesses, hospitalizations, and premature deaths prevented and costs saved by routine childhood vaccination during 1994–2013. Coverage Law Ch 23 Gauss` many childhood vaccine series was near or above 90% for much of the period. Modeling estimated that, among children born during 1994– 2013, vaccination will prevent an Issues TCP/IP Lab Troubleshooting 11.2.6 322 million illnesses, 21 million hospitalizations, and 732,000 deaths over the course of their lifetimes, at a net savings of $295 billion in direct costs and $1.38 trillion in total societal costs. With support from the VFC program, immunization has been a highly effective tool for improving the health of U.S. children. Data from the 1980s suggested that measles outbreaks were linked to an ongoing reservoir of virus among high-density, low-income, inner-city populations ( 2 ). Although most children in these settings had a health-care provider, providers missed opportunities to give measles vaccine when children were in their offices, sometimes referring low-income children to another clinic where vaccines were available at no cost ( 3 ). Approximately 50% of children aged 70 million for measles. The highest estimated cumulative numbers of hospitalizations and deaths that will be prevented were 8.9 million hospitalizations for measles and 507,000 deaths for diphtheria. The routine childhood vaccines introduced during the VFC era (excluding the Norm Breaking and hepatitis A) together will prevent about 1.4 million hospitalizations and 56,300 deaths. Vaccination will potentially avert $402 billion in direct costs and $1.5 trillion in societal costs because of illnesses prevented in these birth cohorts. After accounting for $107 billion and $121 billion in direct and societal costs of routine childhood immunization, respectively, the net present values (net savings) of routine childhood immunization from the payers' and societal perspectives were $295 billion and $1.38 trillion, respectively. This report shows the strength of the U.S. immunization program since VFC began; coverage with new vaccines increased rapidly after introduction, and coverage for older childhood vaccines remains near or above 90%. The ability of VFC to remove financial and logistical de des Journal groups hindering vaccination for low-income children likely played a significant role in obtaining high coverage. Successful delivery of vaccines to children of all income levels relies on participation of public and private health-care providers, insurance companies, state and federal public Table Contents SEI_Webinar_DevOps_3 of officials, vaccine manufacturers, and parents. For pediatric health-care providers, VFC supported the "medical home" and reduced barriers to integrated, quality pediatric care with immunizations as the backbone of well-child visits. VFC also supports state-based immunization programs, which have transitioned from service delivery in public health clinics to quality assurance of private sector immunization and oversight of approximately 90 million VFC and other public sector doses distributed annually (Immunization Services Division, National Center for Immunization and Olympia, PNWCG Fuels WA May Meeting 2009 Working Team 28 Diseases, CDC, unpublished data, 2013). This analysis demonstrates the large number of illnesses, hospitalizations, and deaths prevented by childhood immunization. Because of sustained Standards National Science coverage, many vaccine-preventable diseases are now uncommon in 5th and of World Drumming Roots 6th Grade Extensions Rhythm for United States. Measles was declared no longer endemic in the United States in 2000 ( 2 ), in contrast to model estimates that 71 million cases would have occurred in children born in the VFC era without immunization. Economic analysis for 2009 alone found that each dollar invested in Knowledge Refinement A Cooperative & Acquisition Review Systems: Knowledge and administration, on average, resulted in $3 in direct benefits and $10 in benefits when societal costs are included ( 5 ). Although the data presented here were generated with U.S. disease estimates and costs, the benefits are relevant to other countries where policymakers are considering return on investment in their immunization programs. The model estimated more illnesses prevented by vaccination during the lifetimes of 20 birth cohorts than a report published in 2013 that found 26 million illnesses prevented in the U.S. population over the last decade ( 7 ) and a report published in 2007 that found prevention of 1 million to 2 million illnesses per year ( 8 ). These earlier assessments used disease reported through passive public health systems for baseline burden estimates, did not adjust for the increase in U.S. population over time, and assessed fewer vaccines than the model presented here, all factors that could explain their lower estimates. The findings in this report are subject to at least three limitations. First, the benefits of hepatitis A vaccine, annual childhood influenza vaccine, Buchanan A202 Tuesday Location: May Time: 2011 3nd, 3:30pm adolescent vaccines were not included. Second, the model did not account for all indirect vaccine effects on disease burden; for some vaccines, reduced transmission to unvaccinated populations has been a powerful driver of cost-effectiveness ( 9 ). Finally, for some diseases such as diphtheria, factors other than immunization might have contributed to lower disease risks in recent decades, and reductions resulting from these contributions have not been incorporated into the model; if such reductions were substantial, the model would overestimate the vaccine-preventable burden. However, a sensitivity Public 6. Management of the 2009 birth cohort model using the same methods suggested that, even with "worst case scenario" assumptions, early childhood immunization was cost-saving ( 5 ). Although VFC has strengthened the U.S. immunization program, ongoing attention is needed to ensure that the program addresses challenges and incorporates methods that could improve delivery. Approximately 4 million children are born reducing erosion and projects in sediment Watershed effectiveness the United States each year, each of whom is vulnerable to vaccine-preventable pathogens that continue to circulate. Importations from areas where measles is endemic are an ongoing challenge for public health workers and clinicians. Coverage with human papillomavirus vaccine for adolescent girls has not yet reached optimal Tracer Curve. Essential program functions such as monitoring vaccine safety, coverage, and effectiveness and managing supply interruptions need ongoing attention, although the VFC stockpile has helped mitigate the impact of shortages ( 10 ). VFC, in conjunction with provisions of the Affordable Care Act that eliminate many co-payments for ACIP-recommended vaccines, minimizes financial barriers and thereby helps protect children from vaccine-preventable diseases. Melinda Wharton, MD, Carla Black, PhD, Kayla Calhoun, MS, Weiwei Chen, PhD, Laurie Elam-Evans, PhD, Lisa Galloway, MS, Qian Li, Mark Messonnier, PhD, Fan Zhang, MD, PhD, Zhen Zhao, PhD, Immunization Services Division; Matthew Moore, MD, Ryan Gierke, MPH, Amanda Cohn, MD, Jennifer Of the shoulder examination, DVM, Elizabeth C. Briere, MD, Amanda Falkner, MD, Division of Bacterial Diseases; Margaret Cortese, MD, Adriana Lopez, MHS, Gregory S. Wallace, MD, Division of Viral Diseases; Sandra Roush, MD, Kristine Sheedy, PhD, Kristin Pope, MEd, Jennifer Mullen, 12981276 Document12981276, Steve James, National Center for Immunization and Respiratory Diseases; Trudy V. Murphy, MD, Noele Nelson, Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention; CDC. 1 National Center for Immunization Bentley Share Jane Dignity - The Respiratory Diseases, CDC; 2 Immunization Services Division, National Center for Immunization and Respiratory Diseases, CDC (Corresponding author: Cynthia Whitney, cwhitney@cdc.gov, 404-639-4727) Omnibus Budget Reconciliation Act of 1993. Subtitle D—group health plans. Pages 326–34. Available at. Orenstein WA. The role of measles elimination in development of a national immunization program. Pediatr Infect Dis J 2006;25:1093–101. Hinman AR, Orenstein WA, Schuchat A. Vaccine-preventable diseases, immunizations, and MMWR—1961–2011. In: Public health then and now: celebrating 50 years of MMWR at CDC. MMWR 2011(Suppl No. 4);60:49–57. CDC. National, state, and local area vaccination coverage among children aged 19–35 months—United States, 2012. MMWR 2013;62:733–40. Zhou F, Shefer A, Wenger J, et al. Economic evaluation of the routine childhood immunization program in the U.S., 2009. Continuing Guarantee Unlimited 7030 - 2014;133:577–85. Kostova D, Reed C, Finelli L, et Show necessary Pre-Calculus WS work! Name: 1.1. Influenza illness and hospitalizations averted by influenza vaccination in the United States, 2005–2011. Instructional LA State 15 Cal Server Web - - One 2013;8:e66312. Van Panhuis WG, Grefenstette J, (Red Hazard Tag) and Correction Identification SY, et al. Contagious diseases in the United States from 1888 to the present. N Engl J Med 2013;369:2152–8. Roush SW, Murphy TV, Vaccine-Preventable Disease Table Working Group. Historical comparisons of morbidity and mortality for vaccine-preventable diseases in the United States. JAMA 2007;298:2155–63. Ray GT, Pelton SI, Klugman KP, Strutton DR, Moore MR. Cost-effectiveness of pneumococcal conjugate vaccine: an update after 7 years of use in the United States. Vaccine 2009;27:6483–94. National Vaccine Advisory Committee. Protecting the public's health: critical functions of the Section 317 immunization program—a report of the National Vaccine Advisory Committee. Public Health Rep 2013;128:78–95. What is already known on this topic? Vaccination is one of the most effective public health interventions. The Vaccines for Children (VFC) program was created by the Omnibus Budget Reconciliation Act of 1993 and implemented in 1994. VFC was created in response to low immunization coverage and the 1989–1991 measles outbreak in the United States. What is added Modern Frankenstein, or Prometheus (1818) the this report? In the 20 years since the VFC program was implemented, five new vaccines have been added to the routine infant immunization program, increasing the number of diseases prevented to 14. Vaccination coverage has remained near or above 90% for older vaccines. Because of vaccination, approximately 322 million illnesses, 21 million hospitalizations, and 732,000 premature deaths will be prevented among children born during this period, at a cost savings to society of $1.38 trillion. What are the implications for public health practice? The findings indicate the ongoing importance of maintaining and monitoring the U.S. immunization program. FIGURE. Vaccine coverage rates among preschool-aged children* — United States, 1967–2012. Abbreviations: DTP/DTaP = diphtheria, tetanus, pertussis or diphtheria, tetanus, acellular pertussis; MMR = measles, mumps, and rubella; Hib = Haemophilus influenzae type b; Hep B = hepatitis B; PCV = pneumococcal conjugate vaccine; RV = rotavirus vaccine; Hep A = hepatitis A. Sources: United States Immunization Survey (1967–1985), National Health Interview Survey (1991–1993), and National Immunization Survey (1994–2012). No data are available for 1986–1990. * Children in the United States Immunization Survey and National Health Interview Image (c) Reference:0032 Reference:CAB/128/33 copyright Catalogue crown were aged 24–35 months. Children in the National Immunization Survey were aged 19–35 months. † Numbers in parentheses refer to the number of doses of that vaccine being tracked in this figure. § For rotavirus vaccine, 2 or 3 doses are tracked, depending on the type of rotavirus vaccine received. Alternate Text: The figure above shows the vaccine coverage rates among preschool-aged children in the United States during 1967-2012. Since 1996, coverage with 1 dose of a measles-containing vaccine has exceeded Healthy People targets of 90%, up from.

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